Born On The Fourth Of July

price declines in July, "stick" under the fourth generation cephalosporins and future - the pharmaceutical industry
Learned in early July, lower prices the NDRC, the "stick" will again command the antibiotic in the field, this is the third meeting of antibiotics companies to reduce prices. Cephalosporin Streptomyces is a major force in the field of antibiotics can not reduce prices in the natural immune system. At present, a time when cephalosporins of third and fourth generation for growth and opportunity, downward trend in prices is irreversible, the third and fourth generation cephalosporins, in turn how the development future face? product chain cephalosporins produce corn as raw material first be starch and sugar solution, then the bacteria cephalosporin high and their descendants for the bacteria to the natural fermentation of cephalosporin C as raw material and then synthesize 7-ACA, via semi-synthesis through the transformation of their side chains are different. The cephalosporin antibiotics have become commonly used temporary bed, mainly due to penicillin cephalosporins has not only fine Pharmacology similar characteristics, and low toxicity, indications of clinical needs as best suited to the advantages, such as rest and fungicide combination aminoglycoside can often get a good synergy. Because of these advantages, which makes the field of cephalosporins species star, has a considerable market share of antibiotics and the development dynamic. First, second generation cephalosporins widely accepted by the market, while the third, fourth generation cephalosporins are at the stage of market development for export. Third generation cephalosporins: a glorious future The emergence of third generation cephalosporins, antimicrobial spectrum to more resistance, the resistance has also been enhanced enzyme, although performance leather Gram positive antimicrobial is usually less than the first generation (similar to individual species), but the role of Gram-negative compared to the second generation cephalosporin is the greater. Because of third-generation cephalosporins Clinical Excellence table is made to ceftazidime and ceftriaxone as a representative for third-generation antibiotics cephalosporin cephalosporin fast-growing market and even the variety stars. Contract amount third generation cephalosporin, the rapid growth in the 21st century reflects more severe, such as ceftriaxone, has been developed to the annual consumption of 1,000 tonnes of raw materials to scale, and ceftazidime also showed the accelerated development. The root causes, in addition to the excellent quality of the product itself, but also clinical excellence, gradually expand the market is the API, fast falling prices are not independent. Security is the basic quality of life, cost-effectiveness, I believe that this view is shared by the industry. The third generation cephalosporins, ceftriaxone or ceftazidime, whether in the market today is the best example of excellent performance. fourth generation cephalosporins: lower third-generation cephalosporins against Gram-positive role of weak and can not be used for the control of Staphylococcus aureus, therefore, cefpirome, Cefozopran, cefepime and other fourth-generation cephalosporins should be delivered born. fourth generation cephalosporins clinically serious bacterial infections that most third-generation cephalosporins better results, as cefpirome, not only maintained a third-generation cephalosporins on the powerful role of gram-negative, but also strengthen the Gram-positive antimicrobial activity and to avoid drug resistance peak, particularly Streptococcus, pneumococcus has a strong activity against Staphylococcus aureus, Staphylococcus epidermidis and E.